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Oral Versus Intravenous High-Dose Methylprednisolone for Treatment of Relapses in Patients with Multiple Sclerosis (COPOUSEP):A Randomised, Controlled, Double-Blind,Non-Inferiority Trial
Lancet 386:974-981, LePage,E.,et al, 2015
See this aricle in Pubmed

Article Abstract
Oral administration of high-dose methylprednisolone for 3 days was not inferior to intravenous administration for improvement of disability scores 1 month after treatment and had a similar safety profile. This finding could have implications for access to treatment, patient comfort, and cost, but indication should always be properly considered by clinicians.
 
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intravenous
multiple sclerosis
multiple sclerosis,relapsing
multiple sclerosis,treatment of
steroid
steroid therapy,CNS treatment and complications with
treatment of neurologic disorder

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